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ANSWER: Meta-analyses evaluating the A1C-lowering impact of adding a DPP-4 inhibitor or SGLT2 inhibitor to metformin have shown either no significant differences between the two classes or a small difference (0.11% to 0.17%) in favour of SGLT2 inhibitors

Real-world comparison of mono and dual combination therapies of metformin, sulfonylurea, and dipeptidyl peptidase-4 inhibitors using a common data model: A retrospective observational study

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Upon encountering an antigen, immature DCs transform into mature DCs due to their robust antigen phagocytic capacities

The blood glucose levels during IPGTT were highest in HFD model mice, and the semaglutide or calorie restriction treatment significantly decreased the post-load glucose levels (Fig

[PMC free article: PMC2662372] [PubMed: 19299006] 24